Dengue is caused by a virus of the Flaviviridae family and there are four distinct, but closely related, serotypes of the virus that cause dengue (DENV-1, DENV-2, DENV-3 and DENV-4). Herein we show how the comparative analysis of gene sequence data has shed light on the origin and spread of dengue virus, as well as on the evolutionary processes … There is also evidence that epidemics of illnesses resembling dengue occurred in the 17th century. History of Dengue The first reported epidemics of dengue fever occurred in 1779-1780 in Asia, Africa, and North America; the near simultaneous occurrence of outbreaks on three continents indicates that these viruses and their mosquito vector have had a worldwide … Recovery from infection is believed to provide lifelong immunity against that serotype. Dengue viruses are spread to people through the bite of an infected Aedes species ( Ae. To determine the serotype and genotype of dengue virus (DENV) in Bhutan, we conducted phylogenetic analyses of complete envelope gene sequences. History of Dengue The origins of the word dengue are not clear, but one theory is that it is derived from the Swahili phrase "Ka-dinga pepo", meaning "cramp-like seizure caused by an evil spirit". So, dengue virus is one member of a family of viruses that are mostly transmitted by the bites of mosquitoes or ticks, and several members of this family cause diseases in humans. Dengue virus (DENV) belongs to the family Flaviviridae and the genus Flavivirus and has four different serotypes (DENV1-4) [1, 2].This pathogen is an enveloped virus with icosahedral symmetry and a diameter of approximately 50 nm [3, 4]. Dengue is common in more than 100 countries around the world.

albopictus ) mosquito. Areas with risk of dengue. The Swahili word "dinga" may possibly have its origin in the Spanish word "dengue" meaning fastidious or careful, which would describe the gait of a person suffering the bone pain of dengue fever . Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. Dengue fever is caused by any one of four types of dengue viruses spread by mosquitoes that thrive in and near human lodgings. Nevertheless, scientists' understanding of dengue virus may be simplistic, as rather than distinct antigenic groups, a continuum appears to exist. The earliest record of dengue comes from a Chinese medical encyclopedia dating back to 992 BC [ 14 ]. DENV-2 (Cosmopolitan genotype) predominated in 2004, and DENV-3 (genotype III) predominated in 2005–2006; these viruses were imported from India. aegypti or Ae. aegypti is prevalent in the tropics and sub-tropics and is closely associated with human habitats outside its native range of Africa. However, cross-immunity to the other serotypes after recovery is only partial, and temporary. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. 1. Dengue virus (DENV) belongs to the Flavivirus genus and is transmitted by mosquitoes, such as Aedes albopictus and Ae.

According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease. A brief history of dengue in the Americas Historically, it has not been determined when DENV first appeared in human populations, mainly because the disease is often asymptomatic and is therefore not diagnosed [ 2 ]. DF is an arboviral disease caused by dengue virus (DENV). The primary vector of dengue is the Aedes aegypti mosquito.Ae. Dengue is common in more than 100 countries around the world. The emergence of dengue hemorrhagic fever in most tropical countries has made its control a public health priority, but no vaccines or treatments exist.
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